Explore Our Precision-Engineered Microfluidic Valves: Distribution, Switch or On/Off Valves

Discover our state-of-the-art microfluidic valves with unique precision and accuracy. Our valves are meticulously designed to optimize your experiments and deliver exceptional results:

• Minimized Reagent Consumption and Cost Reduction: Our valves feature a unique geometry that minimizes reagent consumption, leading to significant cost savings for your experiments.
• High Cleanability and Reduced Contamination Risks: Say goodbye to cross-contamination risks and biofilm formation. Our valves are designed for high cleanability, ensuring your experiments remain uncontaminated and reliable.
• Standard Microfluidic Connections for Easy Integration: Integrating our valves into your setup is a breeze. They are compatible with standard fluidic connections, making them a seamless addition to your custom microfluidic experiment.
• High Chemical Compatibility and Mechanical Stability: Our microvalves are built to last. They are available in materials such as PTFE (Polytetrafluoroethylene) and UHMW-PE (Ultra-high-molecular-weight polyethylene), both known for their broad chemical compatibility and mechanical robustness.

Explore Our Valve Types

• Distribution valves

Distribution valves facilitate sequential flow distribution and redirection and enable precise regulation of fluidic pathways.

These valves serve as gatekeepers for various channels. They can be adjusted to divert or halt the flow of liquids, ensuring optimal distribution to different destinations. This functionality is crucial in applications ranging from chemical analysis and medical diagnostics to industrial processes.

• Switch valves

Switch valves serve as dynamic control units that determine the direction of fluid flow, enabling you to manipulate fluids with precision and versatility.

Functioning as traffic regulators for microfluidic channels, switch valves allow fluidic pathways to be opened, closed, or changed, facilitating the controlled movement of liquids. This capability is essential for applications spanning from medical diagnostics and chemical analysis to biotechnology and pharmaceutical research.

A custom switch microfluidic valves design could be required for experiment protocols such as liquid recirculation. For example, using a 2-position 6-port switch valve (VS1-6), it is possible to create a system that recirculates the liquid between two vials, all the while maintaining the flow direction in your flow cell.

• On/Off

On/Off valves serve as gatekeepers that control the flow of fluids within intricate systems. These valves are designed to either allow fluid passage or block it entirely.

Operating on a binary principle, On/Off valves function as switches that can be activated to either open or close the fluidic pathway. This control is essential for a wide range of applications, including sample loading, reagent mixing, and flow interruption.

Critical Advantages of Our Microfluidic Valves

• Ultra low carryover volume and low internal volumes

We provide channels diameters as low as 0.25 mm, decreasing the total volume in the system to save reagent consumption.

Our unique microvalve design can include several port stages, significantly decreasing the internal volume (total volume in the system) and allowing fast liquid switching thanks to its ultra-low carryover volume of 1.5 µl (volume of liquid that will be mixed with the next liquid) compared to other microfluidic valves on the market.

• No dead volumes

Our manufacturing process is performed in-house in our facility located on the EPFL campus in Lausanne, Switzerland. At AMF, we are committed to high-quality standards, and a highly precise degree of material machining, and as a result our microvalves exhibit no dead volume (the small amount of liquid left out of the flow path and stuck in the system). The zero dead volume feature allows less contamination between liquids and can be suitable for demanding protocols especially in biological applications showcasing high levels of sensitivity.

In addition to this ultra-precise manufacturing process, all Advanced Microfluidics microvalves undergo a manual final inspection to ensure the consistently high quality of our products.

• Plug and play

Our microvalves on the RVM Electric Rotary Valve, and the SPM OEM Microdispenser can be easily mounted or exchanged. There are only two screws to dismantle on the motor system. This particularly easy changeover procedure facilitates on-site service as well as preventive maintenance.

Our microfluidic valve ports are designed for high compatibility with standard fluidic connections, allowing them to be easily integrated into your protocol and your custom microfluidic experiment.

• Optimized materials

Our microfluidic valves plugs (or valve rotor) are available in different materials:

• PTFE (Polytetrafluoroethylene, also known as Teflon®). This material is chemically inert and therefore highly compatible with most used solvents, with excellent stress resistance.
• UHMW-PE (Ultra-high-molecular-weight polyethylene). This material has a strong resistance to mechanical movements, and is very tough, with the highest impact strength of any thermoplastic presently made.

Our microfluidic valves seats (or valve stator) are available in different materials:

• PCTFE (Polychlorotrifluoroethylene). This material provides excellent chemical resistance and durability, making it ideal for specific applications.
• PEEK (Polyether Ether Ketone). This material offers exceptional mechanical and thermal properties, making it suitable for demanding microfluidic environments.

Valve specifications
DISTRIBUTION SERIES

ON/OFF SERIES

SWITCH SERIES

Valve heads are interchangeable. Other models available upon request.