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Picto-valve-s24
From 6 to 12 ports valve integrated
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From 25µl to 1000µl capacity
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PTFE / PCTFE
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Ready to use

LSPone Laboratory Syringe Pump

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The LSPone laboratory microfluidic pump is a high-precision dosing system designed for microfluidic academic research applications. The LSPone is the unique combination of a high-precision syringe pump with a low-volume rotary valve. This unique device coupled with the intuitive LSPoneQuick software can aspirate or dispense liquids, control the flow rate, prepare complex mixes, and dilute samples or reagents.

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The ALL-IN-ONE Microfluidic Syringe Pump

AMF’s LSPone is suited for microfluidic automation, by design. The optimized space between the rotary valve and the syringe dramatically reduces the internal volume of the module and leads to optimized carryover volumes. The LSPone offers an optimal flow rate, proficiently diluting samples or reagents from milliliters down to nanoliters. It aspirates or dispenses liquids, controls the flow rate, and prepares complex mixes. This versatile tool can efficiently switch between air and liquid samples, ensuring no leakage due to its superior sealing capabilities.

Plug-and-Play benchtop solution to automate your microfluidic experiment.

  • Wetted Material: The rotary valve’s wetted material is PCTFE (for the valve head), PTFE (valve rotor) and borosilicate glass (for the syringe) ensuring robustness and broad chemical compatibility.
  • Channel Diameter: 500 µm to 1000 µm. The conjunction of small internal channel size with unique AMF geometry allows it to reach extremely low internal volumes which can go as low as 600 nL*. This particular attribute optimizes your operation time, saves material (reagents, test materials and samples) and leads ultimately to reduced cost of operations for your final microfluidic application or instrument.
  • Number of Ports: up to 12 radial ports. The valve’s number of ports will give you the ability to handle multiple fluids (from 6 to 12) within your microfluidic device (or detection chamber) and/or manipulate multiple fluids (sample to be tested, reagents, gases).
  • Syringe volume: 500 µL to 1000 µL. Our high-precision syringes are made of borosilicate glass while the plunger is made of PTFE, making our device compatible with biological samples and a wide range of chemicals.

Advanced Microfluidics unique microfluidic LSPone design:

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  • Integrated sensor: the position sensor is directly integrated into the valve rotor (2) to ensure precise valve positioning and internal channel alignment between the rotor and the stator (2). An automatic procedure at power-up alerts the valve of its precise location.
  • For your motor, choose between the fast model for a port switching speed as low as 150 ms and the low power model to reduce power consumption for better portable device integration and smaller power supply.
  • Ready to use: the LSPone is designed for seamless integration, making it incredibly user-friendly. It comes complete with a USB cable & power supply (5), and intuitive software, ensuring hassle-free setup and operation.
  • High precision syringe pump (3)

Advanced Microfluidics unique LSPoneQuick Software:

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  • The LSPoneQuick allows for seamless control of the LSPone. Its ease of use and simplicity allows you to unleash the full potential of the LSPone for your microfluidic experiment in seconds.
  • We integrated an intuitive script editor that allows you to automate the LSPone functions.

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*Our unique precise valves exhibit an internal volume (port-to-port) down to 600 nL (for a 4 ports switch valves) due to their exceptionally small 0.25 mm diameter channels.

Application and technical notes

Use two simultaneous flow with two LSPone syringe pump for microfluidic droplet generation within a chip.

Learn the technique of rapid prototyping for microfabrication and test the fabrication by observing the flow of 2 liquids using optical microscopy.

Automatic cell culture media management system with microfluidic distribution valves and laboratory syringe pump

Pump specifications

Description Specification
Operating temperature 15 – 40°C (59-104°F)
Operating humidity 20-80%, non condensing
Max. pressure 7 bars (102 psi)
Wetted materials PTFE, PCTFE and borosilicate glass
Dead volume None
Carryover volume 1.5 – 10.2 μL
Plunger travel 30 mm with 96,000 micro-steps for nearly pulseless flow
Plunger resolution Selectable 3,000 steps (standard) / 24,000 steps (high)
Plunger drive Screw drive with linear encoder for step loss detection
Valves configuration Zero-dead-volume multi-port distribution with angular encoder
Tube port fittings Standard 1/4 – 28 UNF, flat-bottom
Cross-contamination Typically from 1/100 to 1/1000 per cleaning cycle
Accuracy < 1% deviation from expected value at full stroke
Electrical interface USB mini, 9–pin D–Sub (other upon request)
Interface USB mini, RS-232, RS-485
Communication type Serial (serial over USB, RS232, RS485)
Power 18 - 24 VDC, 2.2 A peak, 40 W / 18 VDC optimized for battery use
Time for full stroke 2 to 6000 seconds
Dimensions 245 x 143 x 85 mm
Weight 2.2 kg
Graphical user interface MS Windows 7 and later vers.
Certifications CE and CB certified

Valve specifications

Ref. Configuration Wetted materials Internal volume Carryover volume Fluid path diameter Maximum pressure
V-D-2-6-050-C-P 6 ports ultra-low carryover volume PCTFE, PTFE 5.2 μL 1.5 μL 0.5 mm 7 bars
V-D-1-6-050-C-P 6 ports ultra-low carryover volume PCTFE, PTFE 3.5 μL 2.6 μL 0.5 mm 7 bars
V-D-1-8-050-C-P 8 ports ultra-low carryover volume PCTFE, PTFE 3.5 μL 2.6 μL 0.5 mm 7 bars
V-D-1-8-100-C-P or U 8 ports ultra-low carryover volume PCTFE, PTFE or UHMW-PE 14.1 μL 10.2 μL 1 mm 7 bars
V-D-1-10-050-C-P or U 10 ports ultra-low carryover volume PCTFE, PTFE or UHMW-PE 4.5 μL 2.8 μL 0.5 mm 7 bars
V-D-1-10-100-C-P or U 10 ports ultra-low carryover volume PCTFE, PTFE or UHMW-PE 18.1 μL 11 μL 1 mm 7 bars
V-D-1-12-050-C-P or U 12 ports ultra-low carryover volume PCTFE, PTFE or UHMW-PE 4.5 μL 2.8 μL 0.5 mm 7 bars

Other configurations are available upon request.

Syringe specifications

Ref. Volume Plunger material Minimum flow rate Maximum flow rate Minimum dosing volume
S-50-P 50 μL PTFE 0.5 μL/min 1500 μL/min 0.1 μL
S-100-P 100 μL PTFE 1 μL/min 3000 μL/min 0.2 μL
S-250-P 250 μL PTFE 2.5 μL/min 8000 μL/min 0.5 μL
S-500-P or S-500-U 500 μL PTFE or UHMW-PE 5 μL/min 15,000 μL/min 1 μL
S-1000-P 1000 μL PTFE 10 μL/min 30,000 μL/min 2 μL

Chemical compatibility: The wetted materials being PTFE, PCTFE and borosilicate glass, this pump offers exceptional compatibility with most chemicals and biological samples.

LSPOne Pump automates nanoparticle formulation and imaging

Ana Ortiz Perez - PhD TUe (Eindhoven)

AMF valves meet our needs, particularly in terms of control

Bernard Roux - Lab manager Solvay

LSPone aids publications via easy programming and clear manuals

Gilles Ouderbrouckx - Researcher Hasselt University

AMF’s compact products and expert support boost microfluidics

Hana Samet - Engineer AGORA & EPFL Research Center

LSPone excels in aspiration, mixing, and slow-flow setups

Jenny Maner - PhD Student Eawag

We are highly content with our AMF rotary valves’ performance

Maarten Jorna - Mechanical engineer The Sensor Factory

The LSPone pumps perfectly fit our application requirements

Robert Toner - Lead Engineer Sarepta Therapeutics

Custome AMF components allowed us to develop the first online flow cytometer for water monitoring

Simon Kuenzi - CEO bNovate

SPM Microdispenser enhances setup precision and robustness

Théo Mayer - EPFL Master Student EPFL

AMF’s products automate microfluidics with precise control and timely support

Xiaokang LI - Postdoctoral researcher Department of Oncology UNIL CHUV Ludwig Institute for Cancer Research Lausanne Centre de recherche Agora

AMF valves, delicately designed, reflect Swiss precision

Yujing Song - PhD Michigan Univeristy

They trust us

From top-tier academic institutions to pioneering biotech companies, Advanced Microfluidics is the preferred partner for innovative microfluidic solutions. Our track record of excellence and precision has earned us the trust of industry leaders, driving us to push boundaries and redefine possibilities together.

Made in Switzerland
+ 10 years of experience
Short Lead Time